Zengru Wu Selected Research

Androgen Antagonists (Antiandrogens)

5/2007

Crystal structure of the T877A human androgen receptor ligand-binding domain complexed to cyproterone acetate provides insight for ligand-induced conformational changes and structure-based drug design.

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Zengru Wu Research Topics

Disease

3	Prostatic Neoplasms (Prostate Cancer) 07/2012 - 05/2007
2	Acromegaly 01/2021 - 02/2018
2	Neoplasms (Cancer) 07/2012 - 01/2010
1	Body Weight (Weight, Body) 02/2022
1	Weight Loss (Weight Reduction) 02/2022
1	Morbid Obesity 02/2022
1	Obesity 02/2022
1	COVID-19 01/2021
1	Inflammation (Inflammations) 01/2021
1	Familial Dysalbuminemic Hyperthyroxinemia 01/2020
1	Pituitary Diseases (Disease, Anterior Pituitary) 02/2018
1	Osteoporosis 10/2008

Drug/Important Bio-Agent (IBA)

3	Hormones (Hormone)IBA 01/2021 - 10/2008
2	Testosterone (Sustanon)FDA Link 02/2022 - 01/2021
2	Gonadal Steroid Hormones (Sex Hormones)IBA 02/2022 - 01/2021
2	Insulin-Like Growth Factor I (IGF-1)IBA 01/2021 - 02/2018
2	Androgen Receptors (Androgen Receptor)IBA 01/2010 - 10/2008
1	Growth Hormone (Somatotropin)IBA 01/2021
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2021
1	Insulin (Novolin)FDA Link 01/2021
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2021
1	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2020
1	Tubulin ModulatorsIBA 07/2012
1	(3- (1H- indol- 2- yl)phenyl)(1H- indol- 2- yl)methanoneIBA 07/2012
1	Antineoplastic Agents (Antineoplastics)IBA 07/2012
1	indoleIBA 07/2012
1	AndrogensIBA 10/2008
1	Cyproterone AcetateIBA 05/2007
1	Androgen Antagonists (Antiandrogens)IBA 05/2007

Therapy/Procedure

1	Bariatric Surgery 02/2022
1	Therapeutics 01/2010